McAfee Total Protection for Enterprise secures servers, email servers and desktops with automatic signature updates and behavior-based technology to prevent attackers from inserting malicious code into systems. The product also uses signatures and behavior-based techniques to detect and remove rootkits. It filters inbound and outbound email for spam, viruses and inappropriate content.

Total Protection for Enterprise is managed via McAfee ePolicy Orchestrator, which allows administrators to enforce policy, monitor network security and make updates from a single console. The product leverages threat research from McAfee Avert Labs, which tracks emerging threats on a global basis.